The Pediatrics World Conference includes this session on moral challenges and advocacy in pediatric care. Informed consent, end-of-life care, and protection of children are the topics for discussion. Stress is laid on the protection of children's rights and their autonomy. Authors will discuss real-life ethical case examples. Techniques for effective advocacy at the local and international levels will be addressed. This session aims to promote awareness of the ethical environment in pediatrics. It is essential for all clinicians who work with children.